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Current literature generally supports greater resolution imaging from 7T compared to 1.5T or 3T MRI, improving visualization of cerebral microbleeds and white and gray matter, and providing more precise localization for radiotherapy targeting. Results: We reviewed 46 studies (43 human and 3 animal models) which reported clinical usages of UHF MRI in the diagnosis and management of gliomas. Some preclinical animal models are briefly described to demonstrate future usages of ultra-high-field imaging. After removing unrelated studies and those with non-human subjects, only those related to 7T MRI were independently reviewed and summarized for data extraction. Case reports and series, observational clinical trials, and randomized clinical trials written in English were included. Methods: A systematic review in accordance with PRISMA guidelines was performed utilizing PubMed. Objective: Summarize current innovative uses of UHF imaging techniques in glioma diagnostics and treatment. Innovations in ultra-high field (UHF) imaging, namely 7-Tesla magnetic resonance imaging (7T MRI) are advancing preoperative tumor grading, visualization of intratumoral structures, and appreciation of small brain structures and lesions. Importance: Gliomas, tumors of the central nervous system, are classically diagnosed through invasive surgical biopsy and subsequent histopathological study.

6Carle Department of Neurosurgery, Carle Foundation Hospital, Urbana, IL, United States.

5Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Champaign, IL, United States.

4Department of Bioengineering, University of Illinois at Urbana-Champaign, Champaign, IL, United States.

3Carle Illinois Advanced Imaging Center, University of Illinois and Carle Health, Urbana, IL, United States.

2Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Champaign, IL, United States.

1Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Champaign, IL, United States.

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Anderson 2,3, Fan Lam 2,4,5, Tracey Wszalek 2,3, Paul M. Level up your working efficiency and gaming performance in the best way.Annabelle Shaffer 1, Susanna S.

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